Leeds United's first ever league game at the Galpharm Stadium started at rapid pace on a damp pitch.
The only change in the starting line-up from Saturday was Tresor Kandol replacing the injured Jermaine Beckford.
Huddersfield matched Leeds for possession and there were few chances for the Whites in the first half.
United were put on the back foot when Jonathan Douglas received his marching orders for a second yellow card in the 38th minute.
This woke the Terriers fans up and Town pressed their advantage in the hope of a goal before the break. Then a goal mouth incident on the stroke of half-time led to a second yellow card for Huddersfield's Jon Worthington which evened up the teams again.
David Prutton came on for Bradley Johnson in the 70th minute and Jonny Howson was replaced by Andy Hughes three minutes later.
A cross by Joe Skarz was headed into the net by Andy Holdsworth and Town were in front, 1-0.
Seb Carole replaced Kilkenny in the 83rd minute but even with five minutes of extra time United failed to make a breakthrough. Poor crosses and badly taken free-kicks did not help Leeds and the Terriers probably deserved it on the night.
The only good thing was that Walsall lost at home to Bristol Rovers so United retain their play-off position with the four point advantage intact but their game in hand used up.
United have not won at Huddersfield since 1963, although we have not been in the same league for much of the time.
Huddersfield Town 1 Leeds United 0